1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0529R
    Azlocillin (Standard)
    Inhibitor
    Azlocillin (Standard) is the analytical standard of Azlocillin. This product is intended for research and analytical applications. Azlocillin, an antibiotic, is a semisynthetic penicillin, and has broad-spectrum antibacterial activity. Azlocillin is active against drug-tolerant B. burgdorferi sensu stricto JLB31 infection.
    Azlocillin (Standard)
  • HY-182621
    MB4253
    Inhibitor
    MB4253 is an orally active aliphatic amide and schistosomicidal agent. MB4253 acts against Schistosoma mansoni. MB4253 can be used for the research of schistosomiasis.
    MB4253
  • HY-A0106R
    Levamisole (Standard)
    Inhibitor
    Levamisole (Standard) is the analytical standard of Levamisole. This product is intended for research and analytical applications. Levamisole ((-)-Levamisole), an anthelmintic agent with immunomodulatory properties. Levamisole acts as a positive allosteric modulator (PAM) for the α3β2 (EC50=300 μM) and α3β4 (EC50=100 μM) subtype of nAChRs. Orally active.
    Levamisole (Standard)
  • HY-B2029R
    Phosalone (Standard)
    Inhibitor
    Phosalone (Standard) is the analytical standard of Phosalone. This product is intended for research and analytical applications.
    Phosalone (Standard)
  • HY-171190
    ELQ-316
    Inhibitor
    ELQ-316 is an endochinlike quinolone compound and an anti-parasite agent. ELQ-316 demonstrates a great efficacy against acute and chronic experimental toxoplasmosis.
    ELQ-316
  • HY-126392
    Isonardoperoxide
    Inhibitor
    Isonardoperoxide is a potent antimalaria agent with an EC50 of 0.6 μM for Plasnwdium fulciparum malaria.
    Isonardoperoxide
  • HY-130752
    VNI
    Inhibitor
    VNI is an effective inhibitor of CYP51. VNI can inhibit sterol synthesis in Trypanosoma cruzi, exhibiting anti-Trypanosoma cruzi activity.
    VNI
  • HY-B1344R
    Oxantel pamoate (Standard)
    Inhibitor
    Oxantel pamoate (Standard) (Oxantel embonate (Standard)) is the analytical standard of Oxantel pamoate (HY-B1344). This product is intended for research and analytical applications. Oxantel pamoate (Oxantel embonate) is an anthelmintic agent that potently against Trichuris muris. Oxantel pamoate inhibits fumarate reductase (Frd) activity in some pathogenic bacteria and inhibits P. gingivalis homotypic biofilm formation (IC50 of 2.2 μM).
    Oxantel pamoate (Standard)
  • HY-180158
    Antitrypanosomal agent 28
    Inhibitor
    Antitrypanosomal agent 28 (Compound 2a) is a trypanocidal agent. Antitrypanosomal agent 28 effectively inhibits Trypanosoma cruzi by inducing the generation of ROS and mitochondrial damage, with an IC₅₀ of 49.4 μM. Antitrypanosomal agent 28 exhibits broad-spectrum anti-tumor activity against various tumor cell lines, especially being sensitive to leukemia, colon cancer, and breast cancer. Antitrypanosomal agent 28 can be used for research on anti-cancer and anti-trypanosome activities.
    Antitrypanosomal agent 28
  • HY-13735AR
    Quinacrine dihydrochloride (Standard)
    Inhibitor
    Quinacrine (dihydrochloride) (Standard) is the analytical standard of Quinacrine (dihydrochloride). This product is intended for research and analytical applications. Quinacrine (Mepacrine) dihydrochloride is an orally bioavailable antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine dihydrochloride suppresses NF-κB and activate p53 signaling, which results in the induction of the apoptosis.
    Quinacrine dihydrochloride (Standard)
  • HY-W774926
    Permethrin-d6
    Inhibitor
    Permethrin-d6 (NRDC-143-d6) is deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide and a high selectively inhibitor of the Mitochondrial complex I, found in sediment and water samples. Permethrin shows estrogenic in vivo and anti-estrogenic activity in vitro. Permethrin also acts as a neurotoxin affecting neuron membranes by prolonging Sodium channel activation. Permethrin decreases resistance to bacterial infections in medaka (Oryzias latipes).
    Permethrin-d<sub>6</sub>
  • HY-N7236
    Pervicoside B
    Inhibitor
    Pervicoside B is a glycoside C isolated from Neothyone gibbosa sea cucumber. In vitro studies have shown that Pervicoside B has a potent antiparasitic effect against Leishmania mexicana, inhibiting 100% of promastigotes at 5-10 μg/mL. Pervicoside B also exhibits strong antifungal activity against Aspergillus niger, with MIC values ranging from 4.65 to 16.7 μg/mL. Pervicoside B has potential applications in the inhibition of parasitic infections and fungal diseases.
    Pervicoside B
  • HY-173051
    Antiparasitic agent-24
    Inhibitor
    Antiparasitic agent-24 (Compound 14a) is an antiparasitic agent, with EC50s of 0.005 μM (L. maj), 0.069 μM (L. don), 0.82 μM (T. brucei), 4.1 μM (T. cruzi) respectively.
    Antiparasitic agent-24
  • HY-15311R
    Avermectin B1 (Standard)
    Inhibitor
    Avermectin B1 (Standard) is the analytical standard of Avermectin B1. This product is intended for research and analytical applications. Avermectin B1 (Abamectin) is a mixture of two similar segments of avermectin. Avermectin B1 is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy.
    Avermectin B1 (Standard)
  • HY-182347
    LSPN954
    Inhibitor
    LSPN954 is an indole-based peptidomimetic antiplasmodial agent. LSPN954 shows slow-acting inhibitory activity, allowing the initial development of Plasmodium followed by morphological changes. LSPN954 can be used in malaria research.
    LSPN954
  • HY-118606
    LDN-0044878
    Inhibitor
    LDN-0044878 is a PAK3 inhibitor. LDN-0044878 inhibits the proliferation or induces the death of p53-deficient cells. LDN-0044878 exhibits moderate trypanocidal activity against Trypanosoma brucei, but does not directly inhibit the core target Rhodesain. LDN-0044878 can be used in studies related to cervical adenocarcinoma and Trypanosoma brucei infection.
    LDN-0044878
  • HY-180156
    FM-8007
    Inhibitor
    FM-8007 is a potent acaricide. FM-8007 exhibits broad-spectrum efficacy against Tetranychus cinnabarinus, with LC50 values of 1.1 mg/L for adults, 0.25 mg/L for larvae, and 0.85 mg/L for eggs. FM-8007 also provides sustained field control against Panonychus citri. FM-8007 can be used for integrated pest management (IPM).
    FM-8007
  • HY-148269
    AN13762
    Inhibitor
    AN13762 is a benzoxaborole antimalarial agent. AN13762 augments Plasmodium falciparum stress responses. AN13762 acts against cultured and fresh Plasmodium falciparum isolates and in vivo murine malaria models. AN13762 can be used for the research of malaria.
    AN13762
  • HY-B2157R
    Robenidine hydrochloride (Standard)
    Inhibitor
    Robenidine hydrochloride (Standard) is the analytical standard of Robenidine hydrochloride. This product is intended for research and analytical applications. Robenidine hydrochloride is an anticoccidial agent which is also active against MRSA and VRE with MIC50s of 8.1 and 4.7 μM, respectively.
    Robenidine hydrochloride (Standard)
  • HY-W011517R
    2-Fluoroadenosine (Standard)
    Inhibitor
    2-Fluoroadenosine (2FA) is a nucleoside analogue. 2-Fluoroadenosine has antiparasite activity with EC50 value of 0.842 mM for Cryptosporidium parvum. 2-Fluoroadenosine has a highly specific structural basis for MtADK. 2-Fluoroadenosine is commonly used in the study of parasitic conditions.
    2-Fluoroadenosine (Standard)

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